Iglk (AA 101-200) antibody (AbBy Fluor® 750)

Catalog No. ABIN5005179

This Rabbit Polyclonal antibody specifically detects in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for Iglk (AA 101-200) antibody (AbBy Fluor® 750) (ABIN5005179)

Target: Iglk

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details

Binding Specificity: AA 101-200

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IGLK

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Iglk

Background:

Synonyms: ATP:D-hexose 6 phosphotransferase, FGQTL3, GCK, GK, GLK, Glucokinase, Hexokinase D, Hexokinase D, pancreatic isozyme, Hexokinase type IV, Hexokinase-4, Hexokinase-D, HHF3, HK IV, HK4, HXK4_HUMAN, HXKP, LGLK, MODY2.

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009].