Anoctamin 2 antibody (N-Term)

Catalog No. ABIN500972

The Rabbit Polyclonal anti-Anoctamin 2 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect Anoctamin 2 in samples from Human, Mouse and Rat.

Quick Overview for Anoctamin 2 antibody (N-Term) (ABIN500972)

Target: Anoctamin 2 (ANO2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Anoctamin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Anoctamin 2 Antibody

Binding Specificity: N-Term

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: TMEM16B antibody was raised against a 19 amino acid peptide from near the amino terminus of human TMEM16B.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for Anoctamin 2

Target: Anoctamin 2 (ANO2)

Alternative Name: Anoctamin-2

Background: Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.Synonyms: ANO2, C12orf3, TMEM16B, Transmembrane protein 16B

Gene ID: 57101

NCBI Accession: NP_065106