Elastase antibody

Catalog No. ABIN5026899

The Chicken Polyclonal anti-Elastase antibody has been validated for ELISA, WB, IHC and AGG. It is suitable to detect Elastase in samples from Mammalian.

Quick Overview for Elastase antibody (ABIN5026899)

Target: Elastase

Reactivity: Mammalian

Host: Chicken

Clonality: Polyclonal

Conjugate: This Elastase antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Agglutination (AGG)

Product Details anti-Elastase Antibody

Characteristics: IgY-antibody

Purification: Precipitation with ammoniumsulfate , dialyse and fitration

Immunogen: raw, native protein

Isotype: IgY

Application Details

Application Notes: Perform a chessboard titation before the first application

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Target Details for Elastase

Target: Elastase

Background: Secreted by neutrophils and macrophages during inflammation, elastase is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity, destroys bacteria and host tissue. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. It is also an important protease enzyme that when expressed aberrantly can cause emphysema or emphysematous changes. This involves breakdown of the lung structure and increased airspaces.