beta Actin antibody (AA 1-200)

Catalog No. ABIN5027055

This Rabbit Polyclonal antibody specifically detects beta Actin in WB. It exhibits reactivity toward Human.

Quick Overview for beta Actin antibody (AA 1-200) (ABIN5027055)

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Actin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-beta Actin Antibody

Binding Specificity: AA 1-200

Cross-Reactivity: Mouse (Murine)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant Beta actin protein (amino acids 1-200) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 4-6 μg/mL:

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for beta Actin

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Alternative Name: Beta actin

Background: B-actin (ACTB) has traditionally been regarded as an endogenous housekeeping gene and has been widely used as a reference gene/protein in quantifying expression levels in tumors. It supports fundamental cellular processes in healthy and diseased cells including cell adhesion, migration, cytokinesis and maintenance of cell polarity. However, B-actin is closely associated with a variety of cancers and accumulating evidence indicates that B-actin is de-regulated in liver, melanoma, renal, colorectal, gastric, pancreatic, esophageal, lung, breast, prostate, ovarian cancers, leukemia and lymphoma. This protein is generally found to be up-regulated in the majority of tumor cells and tissues.

Molecular Weight: 42 KDa

Gene ID: 6598

UniProt: Q12824

Pathways: Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction