CACTIN
Reactivity: Human, Mouse, Rat
WB, IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 488
Application Notes
WB: 2-4 μg/mL
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target
CACTIN
(Cactin, Spliceosome C Complex Subunit (CACTIN))
Alternative Name
Cactin
Background
CACTIN is a conserved protein, discovered as a novel interactor of Drosophila IkappaB protein Cactus. It is highly conserved during evolution and plays a key role in early embryonic development. It is characterized as a negative regulator of many different developmental processes, but only found to play an immune role in humans. CACTIN localizes to nuclear speckles and colocalizes with known splicing proteins. It binds to a putative component of the spliceosome, major role for CACTIN in splicing.