DRAM antibody (AA 1-230)

Catalog No. ABIN5027168

Product Details anti-DRAM Antibody

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Binding Specificity: AA 1-230

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRAM antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant DRAM protein (amino acids 1-230) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 4-6 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for DRAM

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Alternative Name: DRAM (DRAM1 Products)

Background: DRAM (DNA-damage regulated autophagy modulator 1) with a molecular weight of 26 kDa is a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. It belongs to DRAM/TMEM150 family. This gene is regulated as part of the p53 tumor suppressor pathway. DRAM has a pseudogene on chromosome 4. It is expressed in embryonic tissues and stem cells. DRAM1 is often found to be under-expressed in many tumor types. It has 2 isoforms produced by alternative splicing.

Molecular Weight: 32 kDa

Gene ID: 55332

UniProt: Q8N682