ATP6V1A
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
HRP
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Buffer
50 % glycerol
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Liberman, Bond, Shainheit, Stadecker, Forgac: "Regulated assembly of vacuolar ATPase is increased during cluster disruption-induced maturation of dendritic cells through a phosphatidylinositol 3-kinase/mTOR-dependent pathway." in: The Journal of biological chemistry, Vol. 289, Issue 3, pp. 1355-63, (2014) (PubMed).
Matsuda, Okada, Kodama, Honda, Iida: "A cytotoxic type III secretion effector of Vibrio parahaemolyticus targets vacuolar H+-ATPase subunit c and ruptures host cell lysosomes." in: PLoS pathogens, Vol. 8, Issue 7, pp. e1002803, (2012) (PubMed).
Huang, Chen, Shen, Shen, Guo, Gao, Zou: "Inhibition of activated Stat3 reverses drug resistance to chemotherapeutic agents in gastric cancer cells." in: Cancer letters, Vol. 315, Issue 2, pp. 198-205, (2011) (PubMed).
Chen, Zou, Luo, Cao, Zhang, Zhang, Liu: "Effects and mechanisms of proton pump inhibitors as a novel chemosensitizer on human gastric adenocarcinoma (SGC7901) cells." in: Cell biology international, Vol. 33, Issue 9, pp. 1008-19, (2009) (PubMed).
Target
ATP6V1A
(ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A))