ATP6V1A Products
(ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A))
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This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist. [provided by RefSeq, Jul 2008].
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ATP6V1A Antibodies
High quality antibodies with extensive validation data.
ATP6V1A ELISA Kits
Reliable ELISA kits for a wide range of species.
ATP6V1A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ATP6V1A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (6)
Cat. No.
ABIN513626
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6260133
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
- (2)
Cat. No.
ABIN513625
Quantity
50 μL
Datasheet
Datasheet
Recommended ATP6V1A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5594231
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5594230
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1166508
Quantity
96 tests
Datasheet
Datasheet
Recommended ATP6V1A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346111
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346113
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3075317
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ATP6V1A products
: "Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity." in: eLife, Vol. 7, (2018) (PubMed).: "The V-ATPase accessory protein Atp6ap1b mediates dorsal forerunner cell proliferation and left-right asymmetry in zebrafish." in: Developmental biology, Vol. 407, Issue 1, pp. 115-30, (2016) (PubMed).
: "Regulated assembly of vacuolar ATPase is increased during cluster disruption-induced maturation of dendritic cells through a phosphatidylinositol 3-kinase/mTOR-dependent pathway." in: The Journal of biological chemistry, Vol. 289, Issue 3, pp. 1355-63, (2014) (PubMed).
: "Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder." in: Acta neuropathologica communications, Vol. 2, pp. 25, (2014) (PubMed).
: "V-ATPase proton pumping activity is required for adult zebrafish appendage regeneration." in: PLoS ONE, Vol. 9, Issue 3, pp. e92594, (2014) (PubMed).
: "Hypoxia inducible NOD2 interacts with 3-O-sulfogalactoceramide and regulates vesicular homeostasis." in: Biochimica et biophysica acta, Vol. 1830, Issue 11, pp. 5277-86, (2013) (PubMed).
: "A cytotoxic type III secretion effector of Vibrio parahaemolyticus targets vacuolar H+-ATPase subunit c and ruptures host cell lysosomes." in: PLoS pathogens, Vol. 8, Issue 7, pp. e1002803, (2012) (PubMed).
: "Identifying true protein complex constituents in interaction proteomics: the example of the DMXL2 protein complex." in: Proteomics, Vol. 12, Issue 15-16, pp. 2428-32, (2012) (PubMed).
: "Inhibition of activated Stat3 reverses drug resistance to chemotherapeutic agents in gastric cancer cells." in: Cancer letters, Vol. 315, Issue 2, pp. 198-205, (2011) (PubMed).
: "ErbB2-associated changes in the lysosomal proteome." in: Proteomics, Vol. 11, Issue 14, pp. 2830-8, (2011) (PubMed).
Synonyms and alternative names related to ATP6V1A
ATPase H+ transporting V1 subunit A (ATP6V1A), ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a), ATPase, H+ transporting, lysosomal, V1 subunit Aa (atp6v1aa), ATPase H+ transporting V1 subunit A (Atp6v1a), v-type proton ATPase catalytic subunit A (ANI_1_1468024), v-type proton ATPase catalytic subunit A (AOR_1_602134), vacuolar ATP synthase subunit A (VHA-A), ATPase H+ transporting V1 subunit A L homeolog (atp6v1a.L), vacuolar proton pump 3 (vpp3), Vacuolar H[+] ATPase 68kD subunit 1 (Vha68-1), AI647066, An02g10440, AO090102000349, ATP6A1, Atp6a1, atp6a1, Atp6a2, ATP6V1A, ATP6V1A1, Atp6v1a1, atp6v1a1, atp6v1al, CG12403, Dmel\CG12403, HO68, ho68, V-ATPase, v1a, VA68, va68, vacuolar ATP synthase subunit A, Vha, Vha-68-1, vha67-2, Vha68, vha68-1, Vma1, vma1, VPP2, vpp2, zgc:63516Protein level used designations for ATP6V1A
- ATPase, H+ transporting, lysosomal, subunit A1
- H(+)-transporting two-sector ATPase, subunit A
- H+-transporting ATPase chain A, vacuolar (VA68 type)
- V-ATPase 69 kDa subunit 1
- V-ATPase A subunit 1
- V-ATPase subunit A
- V-type proton ATPase catalytic subunit A
- vacuolar ATP synthase catalytic subunit A, ubiquitous isoform
- vacuolar ATPase isoform VA68
- vacuolar proton pump alpha subunit 1
- vacuolar proton pump subunit alpha
- ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70kD
- ATPase, H+ transporting, lysosomal V1 subunit A
- H(+)-ATPase subunit A
- V-ATPase 69 kDa subunit
- vacuolar H+-ATPase A subunit
- 70-kDa subunit
- ATPase, H+ transporting, V1 subunit A
- ATPase, H+ transporting, V1 subunit A1
- ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha 70 kDa
- ATPase, H+ transporting, lysosomal 70kD, V1 subunit A
- lysosomal 70kDa
- ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A, like
- ATPase, H+ transporting, lysosomal V1 subunit A, like
- A2 isoform of vacuolar H+-ATPase subunit A
- H+ ATPase
- Vacuolar ATP synthase catalytic subunit A
- IDP1607
- IDP1607a
- IDP1607c
- IDP1662
- IDP2575
- IDP2575a
- IDP2575c
- PCO134411
- PCO134411(361)
- PCO134411_ov
- PZA00936
- V-ATPase
- V-type H+-ATPase
- nPZA00936-1
- vacuolar ATPase 69 kDa subunit
- vpp*-U36436
- CG12403-PA
- CG12403-PB
- Vha68-1-PA
- Vha68-1-PB
- vacuolar H[+] ATPase subunit 68-1
- ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
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