MFN2 antibody (AA 661-757)

Catalog No. ABIN523306

This Mouse Monoclonal antibody specifically detects MFN2 in WB, ELISA and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for MFN2 antibody (AA 661-757) (ABIN523306)

Target: MFN2 (Mitofusin 2 (MFN2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MFN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6A8

Product Details anti-MFN2 Antibody

Binding Specificity: AA 661-757

Purpose: Mouse monoclonal antibody raised against a partial recombinant MFN2.

Sequence: FKRQFVEHAS EKLQLVISYT GSNCSHQVQQ ELSGTFAHLC QQVDVTRENL EQEIAAMNKK IEVLDSLQSK AKLLRNKAGW LDSELNMFTH QYLQPSR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MFN2 (NP_055689, 661 a.a. ~ 757 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MFN2 antibody (ABIN523306)

Stacchiotti, Favero, Giugno, Lavazza, Reiter, Rodella, Rezzani: "Mitochondrial and metabolic dysfunction in renal convoluted tubules of obese mice: protective role of melatonin." in: PLoS ONE, Vol. 9, Issue 10, pp. e111141, (2014) (PubMed).

Target Details for MFN2

Target: MFN2 (Mitofusin 2 (MFN2))

Alternative Name: MFN2

Background: Full Gene Name: mitofusin 2
Synonyms: CMT2A,CMT2A2,CPRP1,HSG,KIAA0214,MARF

Gene ID: 9927

NCBI Accession: NM_014874

Pathways: Skeletal Muscle Fiber Development