GRHL2 antibody (AA 1-625)

Catalog No. ABIN529152

This anti-GRHL2 antibody is a Mouse Polyclonal antibody detecting GRHL2 in WB and IF. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for GRHL2 antibody (AA 1-625) (ABIN529152)

Target: GRHL2 (Grainyhead-Like 2 (GRHL2))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This GRHL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GRHL2 Antibody

Binding Specificity: AA 1-625

Purpose: Mouse polyclonal antibody raised against a full-length human GRHL2 protein.

Sequence: MSQESDNNKR LVALVPMPSD PPFNTRRAYT SEDEAWKSYL ENPLTAATKA MMSINGDEDS AAALGLLYDY YKVPRDKRLL SVSKASDSQE DQEKRNCLGT SEAQSNLSGG ENRVQVLKTV PVNLSLNQDH LENSKREQYS ISFPESSAII PVSGITVVKA EDFTPVFMAP PVHYPRGDGE EQRVVIFEQT QYDVPSLATH SAYLKDDQRS TPDSTYSESF KDAATEKFRS ASVGAEEYMY DQTSSGTFQY TLEATKSLRQ KQGEGPMTYL NKGQFYAITL SETGDNKCFR HPISKVRSVV MVVFSEDKNR DEQLKYWKYW HSRQHTAKQR VLDIADYKES FNTIGNIEEI AYNAVSFTWD VNEEAKIFIT VNCLSTDFSS QKGVKGLPLM IQIDTYSYNN RSNKPIHRAY CQIKVFCDKG AERKIRDEER KQNRKKGKGQ ASQTQCNSSS DGKLAAIPLQ KKSDITYFKT MPDLHSQPVL FIPDVHFANL QRTGQVYYNT DDEREGGSVL VKRMFRPMEE EFGPVPSKQM KEEGTKRVLL YVRKETDDVF DALMLKSPTV KGLMEAISEK YGLPVEKIAK LYKKSKKGIL VNMDDNIIEH YSNEDTFILN MESMVEGFKV TLMEI

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: GRHL2 (NP_079191.1, 1 a.a. ~ 625 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GRHL2 antibody (ABIN529152)

Mehrazarin, Chen, Oh, Liu, Kang, Yi, Kim, Shin, Park, Kang: "The p63 Gene Is Regulated by Grainyhead-like 2 (GRHL2) through Reciprocal Feedback and Determines the Epithelial Phenotype in Human Keratinocytes." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19999-20008, (2015) (PubMed).

Dompe, Rivers, Li, Cordes, Schwickart, Punnoose, Amler, Seshagiri, Tang, Modrusan, Davis: "A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 43, pp. E943-51, (2011) (PubMed).

Target Details for GRHL2

Target: GRHL2 (Grainyhead-Like 2 (GRHL2))

Alternative Name: GRHL2

Background: Full Gene Name: grainyhead-like 2 (Drosophila)
Synonyms: BOM,DFNA28,FLJ11172,FLJ13782,MGC149294,MGC149295,TFCP2L3

Gene ID: 79977

NCBI Accession: NM_024915

Pathways: Tube Formation