CHORDC1 antibody (N-Term)

Catalog No. ABIN5514389

Product Details anti-CHORDC1 Antibody

Target: CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHORDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TYHPGVPVFH DALKGWSCCK RRTTDFSDFL SIVGCTKGRH NSEKPPEPVK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against CHRD1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CHRD1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHORDC1

Target: CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))

Alternative Name: CHRD1 (CHORDC1 Products)

Background: CHRD1 regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. It is proposed to act as co-chaperone for HSP90. CHRD1 may play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, it has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. It is involved in stress response. It prevents tumorigenesis.

Alias Symbols: CHORDC1, CHP1,

Protein Interaction Partner: TARS2, XPO5, CDC37L1, CDC37, TOMM34, AHSA1, TUBA1B, TTC4, PPP5C, HSP90AB1, HSP90AA1, FKBP5, FKBP4, BCCIP, NAGK, C11orf58, SUGT1, KYNU, TCEA1, SORD, SMS, PGD, CSE1L, XPO1, UBC, PAK1, CHORDC1,

Protein Size: 332

Gene ID: 26973

NCBI Accession: NP_036256

UniProt: Q9UHD1