Neurexin 1 antibody (C-Term)

Catalog No. ABIN5515512

This Rabbit Polyclonal antibody specifically detects Neurexin 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Neurexin 1 antibody (C-Term) (ABIN5515512)

Target: Neurexin 1 (NRXN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurexin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Neurexin 1 Antibody

Binding Specificity: C-Term

Sequence: RDEGSYHVDE SRNYISNSAQ SNGAVVKEKQ PSSAKSSNKN KKNKDKEYYV

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NRXN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Neurexin 1

Target: Neurexin 1 (NRXN1)

Alternative Name: NRXN1

Background: Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human (NRXN1 and NRXN3). By using alternate promoters, splice sites and exons, predictions of hundreds or even thousands of distinct mRNAs have been made. Most transcripts use the upstream promoter and encode alpha-neurexin isoforms, fewer transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. Alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible.

Alias Symbols: PTHSL2, SCZD17, Hs.22998

Protein Size: 167

Gene ID: 9378

NCBI Accession: NM_138735, NP_620072

UniProt: P58400

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development