POMP antibody (C-Term)

Catalog No. ABIN5515598

This anti-POMP antibody is a Rabbit Polyclonal antibody detecting POMP in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse and Zebrafish (Danio rerio).

Quick Overview for POMP antibody (C-Term) (ABIN5515598)

Target: POMP (Proteasome Maturation Protein (POMP))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POMP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POMP Antibody

Binding Specificity: C-Term

Sequence: EFKAVQQVQR LPFLSSSNLS LDVLRGNDET IGFEDILNDP SQSEVMGEPH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against POMP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human POMP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POMP

Target: POMP (Proteasome Maturation Protein (POMP))

Alternative Name: POMP

Background: The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.

Alias Symbols: POMP, C13orf12, UMP1,

Protein Interaction Partner: SHFM1, PSMA5, PSMA4, PSMA3, PSMA2, PSMG1, PSMB7, PSMB4, PSMB3, PSMB2, PSMA7, UBC, ECT2, DSTN, CPLX1, CD2BP2, UBE2V1, UBE2A, IGBP1, KCNA10, PSMB1, PSMA6, PSMA1, CANX, PSMG2, POMP, CUL1, PSMB10, PSMB9, PSMB8, PSMB6, PSMB5, GRB2,

Protein Size: 141

Gene ID: 51371

NCBI Accession: NP_057016

UniProt: Q9Y244