CYR61 antibody (Middle Region)

Catalog No. ABIN5515924

The Rabbit Polyclonal anti-CYR61 antibody has been validated for WB. It is suitable to detect CYR61 in samples from Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for CYR61 antibody (Middle Region) (ABIN5515924)

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYR61 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CYR61 Antibody

Binding Specificity: Middle Region

Sequence: CEYNSRIYQN GESFQPNCKH QCTCIDGAVG CIPLCPQELS LPNLGCPNPR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CYR61. It was validated on Western Blot.

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CYR61

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYR61

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Alternative Name: CYR61

Background: The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.

Alias Symbols: CCN1, GIG1, IGFBP10

Protein Interaction Partner: UBC, SOX2, UBD, YWHAZ, Mis12, ZWINT, MYC, ITGAV, ITGB5,

Protein Size: 381

Gene ID: 3491

NCBI Accession: NM_001554, NP_001545

UniProt: Q6FI18

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding