CADPS antibody (C-Term)

Catalog No. ABIN5515925

This anti-CADPS antibody is a Rabbit Polyclonal antibody detecting CADPS in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for CADPS antibody (C-Term) (ABIN5515925)

Target: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CADPS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CADPS Antibody

Binding Specificity: C-Term

Sequence: EVVIMEVQGL KSLAPNRIVY CTMEVEGGEK LQTDQAEASK PTVIRRNRRE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CAPS1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CAPS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CADPS

Target: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Alternative Name: CAPS1

Background: This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.

Alias Symbols: CADPS, CAPS, CAPS1, KIAA1121,

Protein Size: 457

Gene ID: 8618

Pathways: Synaptic Vesicle Exocytosis