ECE1 antibody (C-Term)

Catalog No. ABIN5516002

The Rabbit Polyclonal anti-ECE1 antibody has been validated for WB. It is suitable to detect ECE1 in samples from Human.

Quick Overview for ECE1 antibody (C-Term) (ABIN5516002)

Target: ECE1 (Endothelin-Converting Enzyme 1 (ECE1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECE1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ECE1 Antibody

Binding Specificity: C-Term

Sequence: YTRSSPKALN FGGIGVVVGH ELTHAFDDQG REYDKDGNLR PWWKNSSVEA

Characteristics: This is a rabbit polyclonal antibody against ECE1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ECE1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ECE1

Target: ECE1 (Endothelin-Converting Enzyme 1 (ECE1))

Alternative Name: ECE1

Background: The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Alias Symbols: ECE1,

Protein Size: 770

Gene ID: 1889

UniProt: P42892

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling