LETM1 antibody (C-Term)

Catalog No. ABIN5516086

The Rabbit Polyclonal anti-LETM1 antibody has been validated for WB. It is suitable to detect LETM1 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for LETM1 antibody (C-Term) (ABIN5516086)

Target: LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LETM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LETM1 Antibody

Binding Specificity: C-Term

Sequence: EIDILSDACS KLQEQKKSLT KEKEELELLK EDVQDYSEDL QEIKKELSKT

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against LETM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LETM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LETM1

Target: LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

Alternative Name: LETM1

Background: This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19.

Alias Symbols: LETM1,

Protein Interaction Partner: PSMA3, UBC, LATS2, C12orf57, SYNCRIP, ILF3, TBK1, ICT1,

Protein Size: 739

Gene ID: 3954

NCBI Accession: NP_036450

UniProt: O95202