NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 1 (NDUFAF1) (Middle Region) antibody

Catalog No. ABIN5516353

Product Details

Target:

NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 1 (NDUFAF1)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: KPTSALYPFL GIRFAEYSSS LQKPVASPGK ASSQRKTEGD LQGDHQKEVA

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NDUFAF1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target:

NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 1 (NDUFAF1)

Alternative Name: NDUFAF1 (NDUFAF1 Antibody Abstract)

Synonyms: 2410001M24Rik, CGI-65, CIA30, CGI65, Cia30, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1, NADH:ubiquinone oxidoreductase complex assembly factor 1, Ndufaf1, NDUFAF1

Background: This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19.

Alias Symbols: CGI65, CIA30, CGI-65

Protein Size: 327

Gene ID: 51103

NCBI Accession: NM_016013, NP_057097

UniProt: Q9Y375

Pathways: SARS-CoV-2 Protein Interactome