RORC antibody (N-Term)

Catalog No. ABIN5517298

The Rabbit Polyclonal anti-RORC antibody has been validated for . It is suitable to detect RORC in samples from Human, Rat, Cow, Horse, Pig and Saccharomyces cerevisiae.

Quick Overview for RORC antibody (N-Term) (ABIN5517298)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivity: Human, Rat, Cow, Horse, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORC antibody is un-conjugated

Application: Please inquire

Product Details anti-RORC Antibody

Binding Specificity: N-Term

Sequence: DSLHAEVQKQ LQQRQQQQQE PVVKTPPAGA QGADTLTYTL GLPDGQLPLG

Predicted Reactivity: Cow: 92%, Horse: 85%, Human: 100%, Pig: 100%, Rat: 91%, Yeast: 100%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RORG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Alternative Name: RORC

Background: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: TOR, RORG, RZRG, IMD42, NR1F3, RZR-GAMMA

Protein Interaction Partner: EVI2A, NCOA6, EIF3I, CHD4, EIF4EBP1,

Protein Size: 518

Gene ID: 6097

NCBI Accession: NM_001001523, NP_001001523

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway