ZIC4 antibody (C-Term)

Catalog No. ABIN5517778

The Rabbit Polyclonal anti-ZIC4 antibody has been validated for WB. It is suitable to detect ZIC4 in samples from Human, Mouse, Cow, Guinea Pig, Dog, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for ZIC4 antibody (C-Term) (ABIN5517778)

Target: ZIC4 (Zic Family Member 4 (ZIC4))

Reactivity: Human, Mouse, Cow, Guinea Pig, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZIC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZIC4 Antibody

Binding Specificity: C-Term

Sequence: VHTSDKPYTC KVRGCDKCYT HPSSLRKHMK VHGRSPPPSS GYDSATPSAL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ZIC4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ZIC4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZIC4

Target: ZIC4 (Zic Family Member 4 (ZIC4))

Alternative Name: ZIC4

Background: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene.

Alias Symbols: ZIC4,

Protein Size: 334

Gene ID: 84107

NCBI Accession: NP_115529

UniProt: Q8N9L1