NAT1 antibody (C-Term)

Catalog No. ABIN5518780

The Rabbit Polyclonal anti-NAT1 antibody has been validated for WB. It is suitable to detect NAT1 in samples from Human.

Quick Overview for NAT1 antibody (C-Term) (ABIN5518780)

Target: NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NAT1 Antibody

Binding Specificity: AA 172-201, C-Term

Purpose: Anti-NAT1 Antibody Picoband®

Sequence: NEEFLHSDLL EDSKYRKIYS FTLKPRTIED

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-NAT1 Antibody Picoband® (ABIN5518780). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human NAT1, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: N-acetyltransferase 1 (arylamine N-acetyltransferase)". 2. De León, J. H., Vatsis, K. P., Weber, W. W. (2000). "Characterization of naturally occurring and recombinant human N-acetyltransferase variants encoded by NAT1". Molecular Pharmacology. 58 (2): 288-299. 3. Gubin, A. N., Njoroge, J. M., Bouffard, G. G., Miller, J. L. (1999). "Gene Expression in Proliferating Human Erythroid Cells". Genomics. 59(2): 168-177.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for NAT1

Target: NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))

Alternative Name: NAT1

Background:

Synonyms: Arylamine N-acetyltransferase 1,2.3.1.5,Arylamide acetylase 1,Monomorphic arylamine N-acetyltransferase,MNAT,N-acetyltransferase type 1,NAT-1,NAT1,AAC1,

Background: N-acetyltransferase 1 (arylamine N-acetyltransferase) is a protein that in humans is encoded by the NAT1 gene. This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 34 kDa

Gene ID: 9

UniProt: P18440