AKR1B10 antibody (C-Term)

Catalog No. ABIN5518800

This Rabbit Polyclonal antibody specifically detects AKR1B10 in WB, IHC, IF, ICC. It exhibits reactivity toward Human.

Quick Overview for AKR1B10 antibody (C-Term) (ABIN5518800)

Target: AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1B10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-AKR1B10 Antibody

Binding Specificity: AA 285-316, C-Term

Purpose: Anti-AKR1B10 Antibody Picoband®

Sequence: EMATILSFNR NWRACNVLQS SHLEDYPFNA EY

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-AKR1B10 Antibody Picoband® (ABIN5518800). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human AKR1B10.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. Cao D, Fan ST, Chung SS (Jun 1998). "Identification and characterization of a novel human aldose reductase-like gene". J Biol Chem. 273 (19): 11429-35. 2. Hyndman DJ, Flynn TG (Oct 1998). "Sequence and expression levels in human tissues of a new member of the aldo-keto reductase family". Biochim Biophys Acta. 1399(2-3): 198-202.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for AKR1B10

Target: AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))

Alternative Name: AKR1B10

Background:

Synonyms: Aldo-keto reductase family 1 member B10,1.1.1.-,ARL-1,Aldose reductase-like,Aldose reductase-related protein,ARP,hARP,Small intestine reductase,SI reductase,AKR1B10,AKR1B11,

Tissue Specificity: Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.

Background: Aldo-keto reductase family 1 member B10 is an enzyme that in humans is encoded by the AKR1B10 gene. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.

Molecular Weight: 36 kDa

Gene ID: 57016

UniProt: O60218