TMEM240 antibody (AA 1-173)

Catalog No. ABIN5518882

The Rabbit Polyclonal anti-TMEM240 antibody has been validated for WB. It is suitable to detect TMEM240 in samples from Human, Mouse and Rat.

Quick Overview for TMEM240 antibody (AA 1-173) (ABIN5518882)

Target: TMEM240 (Transmembrane Protein 240 (TMEM240))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM240 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMEM240 Antibody

Binding Specificity: AA 1-173

Purpose: Anti-TMEM240 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TM Antibody Picoband® (ABIN5518882). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TMEM240 recombinant protein (Position: M1-L173). Human TMEM240 shares 97.7% amino acid (aa) sequence identity with mouse TMEM240.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Delplanque, J., Devos, D., Huin, V., Genet, A., Sand, O., Moreau, C., Goizet, C., Charles, P., Anheim, M., Monin, M. L., Buee, L., Destee, A., and 9 others. TMEM240 mutations cause spinocerebellar ataxia 21 with mental retardation and severe cognitive impairment. Brain 137: 2657-2663, 2014. the TMEM240 gene maps to chromosome 1p36.33. 2. Devos, D., Schraen-Maschke, S., Vuillaume, I., Dujardin, K., Naze, P., Willoteaux, C., Destee, A., Sablonniere, B. Clinical features and genetic analysis of a new form of spinocerebellar ataxia. Neurology 56: 234-238, 2001.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for TMEM240

Target: TMEM240 (Transmembrane Protein 240 (TMEM240))

Alternative Name: TMEM240

Background:

Synonyms: Transmembrane protein 240,TMEM240,C1orf70,

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: TMEM240 is a small, highly conserved transmembrane protein expressed in brain. The TMEM240 gene maps to chromosome 1p36.33. This gene encodes a transmembrane-domain containing protein found in the brain and cerebellum. Mutations in this gene result in spinocerebellar ataxia 21.

Molecular Weight: 19 kDa

Gene ID: 339453