Relaxin 1 antibody

Catalog No. ABIN5519057

Product Details anti-Relaxin 1 Antibody

Target: Relaxin 1 (RLN1)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Relaxin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Anti-Relaxin 1/RLN1 Antibody Picoband®

Sequence: VAAKWKDDVI KLCGRELVRA QIAICGMSTW S

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Relaxin 1/RLN1 Antibody Picoband® (ABIN5519057). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Relaxin 1, which shares 45.2% amino acid (aa) sequence identity with mouse Relaxin 1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
1. Hsu, S. Y., Nakabayashi, K., Nishi, S., Kumagai, J., Kudo, M., Sherwood, O. D., Hsueh, A. J. W. Activation of orphan receptors by the hormone relaxin. Science 295: 671-674, 2002. 2. Schwabe, C., Bullesbach, E. E. Relaxin: structures, functions, promises, and nonevolution. FASEB J. 8: 1152-1160, 1994.

Comment:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Relaxin 1

Target: Relaxin 1 (RLN1)

Alternative Name: RLN1 (RLN1 Products)

Background:

Synonyms: Prorelaxin H1, Relaxin B chain, Relaxin A chain, RLN1,

Tissue Specificity: Prostate. Not expressed in placenta, decidua or ovary.

Background: Relaxin 1 is a member of relaxin-like peptide family. Relaxin gene maps to human chromosome 19 near D19Mit23. Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. Relaxin widens the pubic bone and facilitates labor, it also softens the cervix (cervical ripening), and relaxes the uterine musculature. However, its significance may reach much further. Relaxin affects collagen metabolism, inhibiting collagen synthesis and enhancing its breakdown by increasing matrix metalloproteinases. It also enhances angiogenesis and is a potent renal vasodilator.

Molecular Weight: 21 kDa

Gene ID: 6013

UniProt: P04808