R-RAS2 antibody
Reactivity: Human
ELISA, FACS, ICC, WB
Host: Mouse
Monoclonal
EM-50
unconjugated
-
- Target
- R-RAS2
- Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- Un-conjugated
- Application
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
- Purpose
- Anti-R-RAS2 Purified
- Specificity
- The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Immunogen
- Human TC21
- Clone
- EM-50
- Isotype
- IgG1 kappa
-
anti-R-RAS2 antibody (PE)
Reactivity: Human ICFC Host: Mouse Monoclonal EM-50 PE
-
- Application Notes
- Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
- Restrictions
- For Research Use only
-
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
-
- Target
- R-RAS2
- Background
- RAS related 2,R-Ras2 / TC21 is the only member of R-Ras family of small GTPases that shows transforming activities similar to H-Ras, N-Ras, and K-Ras, and it is also structurally similar to them. R-Ras2 seems to play an important role in activating signal transduction pathways that control cell proliferation. Its mutations are associated with the growth of certain tumors, but also overexpression of the wild type form of R-Ras2 has been frequently detected in various carcinomas. Pseudogenes of R-Ras2 gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.,TC21, RRAS2
- Gene ID
- 22800
- UniProt
- P62070
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