COPZ1 antibody (N-Term)

Catalog No. ABIN5530937

This Rabbit Polyclonal antibody specifically detects COPZ1 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for COPZ1 antibody (N-Term) (ABIN5530937)

Target: COPZ1 (Coatomer Protein Complex, Subunit zeta 1 (COPZ1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPZ1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COPZ1 Antibody

Binding Specificity: AA 24-53, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COPZ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human COPZ1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for COPZ1

Target: COPZ1 (Coatomer Protein Complex, Subunit zeta 1 (COPZ1))

Alternative Name: COPZ1

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

Molecular Weight: 20 kDa

Gene ID: 22818

UniProt: P61923