ABCC12 antibody (AA 723-752)

Catalog No. ABIN5534921

This Rabbit Polyclonal antibody specifically detects ABCC12 in WB and IHC (p). It exhibits reactivity toward Mouse.

Quick Overview for ABCC12 antibody (AA 723-752) (ABIN5534921)

Target: ABCC12 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCC12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ABCC12 Antibody

Binding Specificity: AA 723-752

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the Central region of human ABCC12.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ABCC12

Target: ABCC12 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12))

Alternative Name: ABCC12

Background: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.

Molecular Weight: 152 kDa

Gene ID: 94160

UniProt: Q96J65