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ACTN1 antibody (AA 1-249)

This Mouse Monoclonal antibody specifically detects ACTN1 in WB, FACS and EIA. It exhibits reactivity toward Human.
Catalog No. ABIN5539997

Quick Overview for ACTN1 antibody (AA 1-249) (ABIN5539997)

Target

See all ACTN1 Antibodies
ACTN1 (Actinin, alpha 1 (ACTN1))

Reactivity

  • 58
  • 21
  • 18
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human

Host

  • 47
  • 10
  • 1
Mouse

Clonality

  • 49
  • 9
Monoclonal

Conjugate

  • 37
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ACTN1 antibody is un-conjugated

Application

  • 39
  • 25
  • 19
  • 14
  • 8
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone

AT1D10
  • Binding Specificity

    • 10
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-249

    Purification

    Protein-A affinity chromatography

    Immunogen

    Recombinant human ACTN1 (1-249aa) purified from E. coli.

    Isotype

    IgG2a
  • Application Notes

    The antibody has been tested by ELISA, Western blot analysis and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    Expiry Date

    12 months
  • Target

    ACTN1 (Actinin, alpha 1 (ACTN1))

    Alternative Name

    alpha-actinin-1,actn1

    Background

    ACTN1 also known as Actinin, alpha 1. ACTN1 functions as an actin-binding-protein. ACTN1 determines the motility of keratinocytes by regulating the organization of the actin cytoskeleton, focal adhesion, and hemidesmosome proteins complexes, thereby modulating cell speed, lamellipodial dymics, and directed migration.

    UniProt

    P12814

    Pathways

    Cell-Cell Junction Organization
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