SNAIL antibody (AA 1-264)

Catalog No. ABIN5542116

The Mouse Monoclonal anti-SNAIL antibody has been validated for WB and EIA. It is suitable to detect SNAIL in samples from Human.

Quick Overview for SNAIL antibody (AA 1-264) (ABIN5542116)

Target: SNAIL (SNAI1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SNAIL antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT2D5

Product Details anti-SNAIL Antibody

Binding Specificity: AA 1-264

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human SNAI1 (1-264aa) purified from E. coli

Isotype: IgG2b

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for SNAIL

Target: SNAIL (SNAI1)

Alternative Name: snai1

Background: SNAI1, also known as Snail homolog 1, is involved in the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. This protein binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. Both SNAI1 and SLUG belong to the snail C2H2-type zinc-finger protein family. SLUG is a transcriptional repressor, involved in the generation and migration of neural crest cells. SNAI1 is expressed in mesenchymal, epithelial cell lines and highest expression in kidney.

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling