EDAR antibody (AA 27-448)

Catalog No. ABIN5542249

This anti-EDAR antibody is a Mouse Monoclonal antibody detecting EDAR in WB and EIA. Suitable for Human.

Quick Overview for EDAR antibody (AA 27-448) (ABIN5542249)

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EDAR antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT19E8

Product Details anti-EDAR Antibody

Binding Specificity: AA 27-448

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human EDAR (27-448aa) purified from E.coli.

Isotype: IgG2a

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for EDAR

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Alternative Name: edar

Background: Tumor necrosis factor receptor superfamily member EDAR is a protein that in humans is encoded by the EDAR gene. EDAR and other genes provide instructions for making proteins that work together during embryonic development. These proteins form part of a signaling pathway that is critical for the interaction between two cell layers, the ectoderm and the mesoderm. In the early embryo, these cell layers form the basis for many of the body's organs and tissues. Ectoderm-mesoderm interactions are essential for the proper formation of several structures that arise from the ectoderm, including the skin, hair, nails, teeth, and sweat glands.

UniProt: Q9UNE0

Pathways: Tube Formation, Ubiquitin Proteasome Pathway