BMP4 antibody (AA 277-408)

Catalog No. ABIN5542285

This anti-BMP4 antibody is a Mouse Monoclonal antibody detecting BMP4 in WB, ELISA and ICC. Suitable for Human and Rat.

Quick Overview for BMP4 antibody (AA 277-408) (ABIN5542285)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This BMP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 3C11H8

Product Details anti-BMP4 Antibody

Binding Specificity: AA 277-408

Purpose: BMP4 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human BMP4 (AA: 277-408) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/100 - 1/500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Alternative Name: BMP4

Background: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Molecular Weight: 46.5 kDa

Gene ID: 652

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development