BUB1 antibody (AA 1-130)

Catalog No. ABIN5542587

The Mouse Monoclonal anti-BUB1 antibody has been validated for ELISA, FACS. It is suitable to detect BUB1 in samples from Human.

Quick Overview for BUB1 antibody (AA 1-130) (ABIN5542587)

Target: BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BUB1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 1A11C7

Product Details anti-BUB1 Antibody

Binding Specificity: AA 1-130

Purpose: BUB1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human BUB1 (AA: 1-130) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for BUB1

Target: BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

Alternative Name: BUB1

Background: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

Molecular Weight: 122.4 kDa

Gene ID: 699

UniProt: O43683