GAD65 antibody (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa)) (AA 1-100) Primary Antibody
GAD2
Reactivity: Human
ELISA, FACS, ICC, IHC, WB
Host: Mouse
Monoclonal
5D9G12
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Catalog No. ABIN5542620
$448.80
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0.1 mg
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- Target
- Binding Specificity
- AA 1-100
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
- Conjugate
- This GAD65 antibody is un-conjugated
- Application
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
- Immunogen
- Purified recombinant fragment of human GAD2 (AA 1-100) expressed in E. Coli.
- Clone
- 5D9G12
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.05 % sodium azide
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- Alternative Name
- GAD2 (GAD2 Antibody Abstract)
- Synonyms
- GAD65, gad65, F12P19.12, F12P19_12, GLUTAMATE DECARBOXYLASE 2, glutamate decarboxylase 2, zgc:112198, 6330404F12Rik, GAD(65), Gad-2, glutamate decarboxylase 2, glutamate decarboxylase 1, glutamic acid decarboxylase 2, GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
- Background
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.,
- Molecular Weight
- 65.4kDa
- HGNC
- 2572
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