GART antibody (AA 1-433)

Catalog No. ABIN560998

This Mouse Monoclonal antibody specifically detects GART in WB, IF, IP, ELISA and IHC (p). It exhibits reactivity toward Human and has been mentioned in 5+ publications.

Quick Overview for GART antibody (AA 1-433) (ABIN560998)

Target: GART (Phosphoribosylglycinamide Formyltransferase (GART))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GART antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4D6-1D5

Product Details anti-GART Antibody

Binding Specificity: AA 1-433

Purpose: Mouse monoclonal antibody raised against a full length recombinant GART.

Sequence: MAARVLIIGS GGREHTLAWK LAQSHHVKQV LVAPGNAGTA CSEKISNTAI SISDHTALAQ FCKEKKIEFV VVGPEAPLAA GIVGNLRSAG VQCFGPTAEA AQLESSKRFA KEFMDRHGIP TAQWKAFTKP EEACSFILSA DFPALVVKAS GLAAGKGVIV AKSKEEACKA VQEIMQEKAF GAAGETIVIE ELLDGEEVSC LCFTDGKTVA PMPPAQDHKR LLEGDGGPNT GGMGAYCPAP QVSNDLLLKI KDTVLQRTVD GMQQEGTPYT GILYAGIMLT KNGPKVLEFN CRFGDPECQV ILPLLKSDLY EVIQSTLDGL LCTSLPVWLE NHTALTVVMA SKGYPGDYTK GVEITGFPEA QALGLEVFHA GTALKNGKVV THGGRVLAVT AIRENLISAL EEAKKGLAAI KFEGAIYRKD VGFRAIAFLQ QPR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GART (AAH38958.1, 1 a.a. ~ 433 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GART antibody (ABIN560998)

Baresova, Krijt, Skopova, Souckova, Kmoch, Zikanova: "CRISPR-Cas9 induced mutations along de novo purine synthesis in HeLa cells result in accumulation of individual enzyme substrates and affect purinosome formation." in: Molecular genetics and metabolism, Vol. 119, Issue 3, pp. 270-277, (2016) (PubMed).

Genovese, Gualandi, Taddia, Marverti, Pirondi, Marraccini, Perco, Pelà, Guerrini, Amoroso, Esposito, Martello, Ponterini, DArca, Costi: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." in: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).

Banerjee, Ghosh, Chatterjee, Sinha, Nandagopal: "No Evidence for Mutations that Deregulate GARS-AIRS-GART Protein Levels in Children with Down Syndrome." in: Indian journal of clinical biochemistry : IJCB, Vol. 27, Issue 1, pp. 46-51, (2013) (PubMed).

Noelker, Schwake, Balzer-Geldsetzer, Bacher, Popp, Schlegel, Eggert, Oertel, Klockgether, Dodel: "Differentially expressed gene profile in the 6-hydroxy-dopamine-induced cell culture model of Parkinson's disease." in: Neuroscience letters, Vol. 507, Issue 1, pp. 10-5, (2012) (PubMed).

Field, Anguera, Page, Stover: "5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887." in: Archives of biochemistry and biophysics, Vol. 481, Issue 2, pp. 145-50, (2009) (PubMed).

Target Details for GART

Target: GART (Phosphoribosylglycinamide Formyltransferase (GART))

Alternative Name: GART

Background: Full Gene Name: phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Synonyms: AIRS,GARS,GARTF,MGC47764,PAIS,PGFT,PRGS

Gene ID: 2618