Neuropilin 1 antibody (AA 22-644)

Catalog No. ABIN5611190

This Mouse Monoclonal antibody specifically detects Neuropilin 1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for Neuropilin 1 antibody (AA 22-644) (ABIN5611190)

Target: Neuropilin 1 (NRP1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neuropilin 1 antibody is un-conjugated

Application: ELISA

Clone: 5H11G6

Product Details anti-Neuropilin 1 Antibody

Binding Specificity: AA 22-644

Purpose: NRP1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human NRP1 (AA: 22-644) expressed in HEK293 cells.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Neuropilin 1

Target: Neuropilin 1 (NRP1)

Alternative Name: NRP1

Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Molecular Weight: 103.1 kDa

Gene ID: 8829

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals