ATG7 antibody (AA 558-703)
Quick Overview for ATG7 antibody (AA 558-703) (ABIN5611295)
Target
See all ATG7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Binding Specificity
- AA 558-703
-
Purpose
- ATG7 Antibody
-
Purification
- Purified antibody
-
Immunogen
- Purified recombinant fragment of human ATG7 (AA: 558-703) expressed in E. Coli.
-
Isotype
- IgG2b
-
-
-
-
Application Notes
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
-
Alternative Name
- ATG7
-
Background
-
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
-
Molecular Weight
- 78 kDa
-
UniProt
- O95352
-
Pathways
- Response to Water Deprivation, Autophagy
Target
-