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SPR antibody (AA 164-260)

This Mouse Polyclonal antibody specifically detects SPR in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.
Catalog No. ABIN562987

Quick Overview for SPR antibody (AA 164-260) (ABIN562987)

Target

See all SPR Antibodies
SPR (Sepiapterin Reductase (SPR))

Reactivity

  • 54
  • 28
  • 18
  • 3
  • 1
  • 1
  • 1
Human

Host

  • 44
  • 11
Mouse

Clonality

  • 46
  • 9
Polyclonal

Conjugate

  • 28
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPR antibody is un-conjugated

Application

  • 48
  • 17
  • 13
  • 13
  • 8
  • 7
  • 6
  • 6
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Binding Specificity

    • 15
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 164-260

    Purpose

    Mouse polyclonal antibody raised against a partial recombinant SPR.

    Sequence

    FKGWALYCAG KAARDMLFQV LALEEPNVRV LNYAPGPLDT DMQQLARETS VDPDMRKGLQ ELKAKGKLVD CKVSAQKLLS LLEKDEFKSG AHVDFYD

    Cross-Reactivity

    Human

    Characteristics

    Antibody Reactive Against Recombinant Protein.

    Immunogen

    SPR (NP_003115, 164 a.a. ~ 260 a.a) partial recombinant protein with GST tag.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    50 % glycerol

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Balasubramanian, Deng, Doudney, Hampton, Kennedy: "Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line." in: Neuropharmacology, Vol. 99, pp. 79-88, (2015) (PubMed).

  • Target

    SPR (Sepiapterin Reductase (SPR))

    Alternative Name

    SPR

    Background

    Full Gene Name: sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
    Synonyms: SDR38C1

    Gene ID

    6697

    NCBI Accession

    NM_003124

    Pathways

    Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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