SPR antibody (AA 164-260)
This Mouse Polyclonal antibody specifically detects SPR in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.
Quick Overview for SPR antibody (AA 164-260) (ABIN562987)
Target
See all SPR Antibodies
SPR
(Sepiapterin Reductase (SPR))
Reactivity
Human
Host
Mouse
Clonality
Polyclonal
Conjugate
This SPR antibody is un-conjugated
Application
Western Blotting (WB), ELISA
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Binding Specificity
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AA 164-260
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Purpose
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Mouse polyclonal antibody raised against a partial recombinant SPR.
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Sequence
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FKGWALYCAG KAARDMLFQV LALEEPNVRV LNYAPGPLDT DMQQLARETS VDPDMRKGLQ ELKAKGKLVD CKVSAQKLLS LLEKDEFKSG AHVDFYD
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Cross-Reactivity
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Human
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Characteristics
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Antibody Reactive Against Recombinant Protein.
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Immunogen
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SPR (NP_003115, 164 a.a. ~ 260 a.a) partial recombinant protein with GST tag.
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Application Notes
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Optimal working dilution should be determined by the investigator.
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Restrictions
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For Research Use only
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Format
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Liquid
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Buffer
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50 % glycerol
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Handling Advice
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Aliquot to avoid repeated freezing and thawing.
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Storage
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-20 °C
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Storage Comment
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Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Balasubramanian, Deng, Doudney, Hampton, Kennedy: "Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line." in: Neuropharmacology, Vol. 99, pp. 79-88, (2015) (PubMed).
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Target
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SPR
(Sepiapterin Reductase (SPR))
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Alternative Name
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SPR
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Background
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Full Gene Name: sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Synonyms: SDR38C1
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Gene ID
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6697
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NCBI Accession
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NM_003124
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Pathways
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Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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