TOPORS antibody (AA 98-205)

Catalog No. ABIN564418

This Mouse Monoclonal antibody specifically detects TOPORS in WB, ELISA, IHC (p) and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for TOPORS antibody (AA 98-205) (ABIN564418)

Target: TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TOPORS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: 5G11

Product Details anti-TOPORS Antibody

Binding Specificity: AA 98-205

Purpose: Mouse monoclonal antibody raised against a partial recombinant TOPORS.

Sequence: SPDSKCPICL DRFDNVSYLD RCLHKFCFRC VQEWSKNKAE CPLCKQPFDS IFHSVRAEDD FKEYVLRPSY NGSFVTPDRR FRYRTTLTRE RNASVYSPSG PVNRRTTT

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TOPORS (NP_005793, 98 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TOPORS antibody (ABIN564418)

Hackbarth, Galvez-Peralta, Dai, Loegering, Peterson, Meng, Karnitz, Kaufmann: "Mitotic phosphorylation stimulates DNA relaxation activity of human topoisomerase I." in: The Journal of biological chemistry, Vol. 283, Issue 24, pp. 16711-22, (2008) (PubMed).

Target Details for TOPORS

Target: TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))

Alternative Name: TOPORS

Background: Full Gene Name: topoisomerase I binding, arginine/serine-rich
Synonyms: LUN,P53BP3,RP31,TP53BPL

Gene ID: 10210

NCBI Accession: NM_005802

Pathways: Maintenance of Protein Location