Thymic Stromal Lymphopoietin antibody

Catalog No. ABIN5647286

This anti-Thymic Stromal Lymphopoietin antibody is a Rabbit Polyclonal antibody detecting Thymic Stromal Lymphopoietin in WB and ELISA (Capture). Suitable for Human and Mouse.

Quick Overview for Thymic Stromal Lymphopoietin antibody (ABIN5647286)

Target: Thymic Stromal Lymphopoietin (TSLP)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thymic Stromal Lymphopoietin antibody is un-conjugated

Application: Western Blotting (WB), ELISA (Capture)

Product Details anti-Thymic Stromal Lymphopoietin Antibody

Purification: Antigen affinity purified

Immunogen: Amino acids KVTTNKCLEQVSQLQGLWRRFNRPLLKQQ were used as the immunogen for the TSLP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TSLP antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the TSLP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Thymic Stromal Lymphopoietin

Target: Thymic Stromal Lymphopoietin (TSLP)

Alternative Name: TSLP

Background: Thymic stromal lymphopoietin, also called TSLP is a protein belonging to the cytokine family. This gene is mapped to 5q22.1. It encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2(TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases.

UniProt: Q969D9