MLLT11 antibody (AA 1-90)

Catalog No. ABIN564754

This Mouse Monoclonal antibody specifically detects MLLT11 in ELISA and WB. It exhibits reactivity toward Human and has been mentioned in 5+ publications.

Quick Overview for MLLT11 antibody (AA 1-90) (ABIN564754)

Target: MLLT11 (Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MLLT11 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: 2A9-1B7

Product Details anti-MLLT11 Antibody

Binding Specificity: AA 1-90

Purpose: Mouse monoclonal antibody raised against a full length recombinant AF1Q.

Sequence: MRDPVSSQYS SFLFWRMPIP ELDLSELEGL GLSDTATYKV KDSSVGKMIG QATAADQEKN PEGDGLLEYS TFNFWRAPIA SIHSFELDLL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: AF1Q (AAH09624, 1 a.a. ~ 90 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MLLT11 antibody (ABIN564754)

Yamada, Clark, Iulianella: "MLLT11/AF1q is differentially expressed in maturing neurons during development." in: Gene expression patterns : GEP, Vol. 15, Issue 2, pp. 80-7, (2014) (PubMed).

Tiberio, Cavadini, Callari, Daidone, Appierto: "AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells." in: PLoS ONE, Vol. 7, Issue 6, pp. e39968, (2012) (PubMed).

Parcelier, Maharzi, Delord, Robledo-Sarmiento, Nelson, Belakhdar-Mekid, Pla, Kuranda, Parietti, Goodhardt, Legrand, Bernstein, Gluckman, Sigaux, Canque: "AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway." in: Blood, Vol. 118, Issue 7, pp. 1784-96, (2011) (PubMed).

Chang, Li, Hou, Wu, Lu, Di, Jin, Ou, Shen, Shao: "Identification of the functional role of AF1Q in the progression of breast cancer." in: Breast cancer research and treatment, Vol. 111, Issue 1, pp. 65-78, (2008) (PubMed).

Co, Tsang, Wong, Cheung, Tsang, Kong, Kwok: "Oncogene AF1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway." in: Molecular cancer therapeutics, Vol. 7, Issue 10, pp. 3160-8, (2008) (PubMed).

Target Details for MLLT11

Target: MLLT11 (Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))

Alternative Name: MLLT11

Background: Full Gene Name: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 11
Synonyms: AF1Q,RP11-316M1.10

Gene ID: 10962