FGA antibody (AA 687-727)

Catalog No. ABIN5647558

The Rabbit Polyclonal anti-FGA antibody has been validated for WB. It is suitable to detect FGA in samples from Human and Rat.

Quick Overview for FGA antibody (AA 687-727) (ABIN5647558)

Target: FGA (Fibrinogen alpha Chain (FGA))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGA Antibody

Binding Specificity: AA 687-727

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: Amino acids 687-727 (RTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVE-human) were used as the immunogen for the Fibrinogen alpha chain antibody. This sequence is specific to the alpha-E isoform and not found in the alpha isoform.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Fibrinogen alpha chain antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Fibrinogen alpha chain antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FGA

Target: FGA (Fibrinogen alpha Chain (FGA))

Background: Fibrinogen alpha chain is a protein that in humans is encoded by the FGA gene. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.

UniProt: P02671