ACOX1
Reactivity: Human
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IHC (Paraffin): 1:10-1:50
Restrictions
For Research Use only
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the ACOX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
ACOX1
(Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))
Alternative Name
ACOX1 / Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1 Products)
Background
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.