HECA antibody (AA 434-543)

Catalog No. ABIN565651

This Mouse Polyclonal antibody specifically detects HECA in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for HECA antibody (AA 434-543) (ABIN565651)

Target: HECA (Headcase Homolog (HECA))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This HECA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HECA Antibody

Binding Specificity: AA 434-543

Purpose: Mouse polyclonal antibody raised against a partial recombinant HECA.

Sequence: CHLQGRLMHL YAVCVDCLEG VHKIICIKCK SRWDGSWHQL GTMYTYDILA ASPCCQARLN CKHCGKPVID VRIGMQYFSE YSNVQQCPHC GNLDYHFVKP FSSFKVLEAY

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HECA (NP_057301, 434 a.a. ~ 543 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-HECA antibody (ABIN565651)

Dowejko, Bauer, Bauer, Müller-Richter, Reichert: "The human HECA interacts with cyclins and CDKs to antagonize Wnt-mediated proliferation and chemoresistance of head and neck cancer cells." in: Experimental cell research, Vol. 318, Issue 5, pp. 489-99, (2012) (PubMed).

Dowejko, Bauer, Müller-Richter, Reichert: "The human homolog of the Drosophila headcase protein slows down cell division of head and neck cancer cells." in: Carcinogenesis, Vol. 30, Issue 10, pp. 1678-85, (2009) (PubMed).

Target Details for HECA

Target: HECA (Headcase Homolog (HECA))

Alternative Name: HECA

Background: Full Gene Name: headcase homolog (Drosophila)
Synonyms: HDC,HDCL,HHDC,dJ225E12.1

Gene ID: 51696

NCBI Accession: NM_016217