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Recombinant Amyloid beta (4-10) (AA 1-42) antibody

Reactivity: Human ELISA, IHC (p), WB Host: Mouse Monoclonal WO2 unconjugated Recombinant Antibody
Catalog No. ABIN5668013
  • Target
    Amyloid beta (4-10)
    Antibody Type
    Recombinant Antibody
    Binding Specificity
    AA 1-42
    Reactivity
    Human
    Host
    Mouse
    Clonality
    Monoclonal
    Application
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purpose
    Anti-Amyloid beta (aa 4-10) [WO2], Mouse IgG2a, kappa
    Specificity
    Recognises amino acid residues 4-10 of human Amyloid β.
    Characteristics

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    Purification
    Protein A affinity purified
    Immunogen
    Synthetic peptides, corresponding to amino acids 1-42 of human beta amyloid, conjugated to KLH.
    Clone
    WO2
    Isotype
    IgG2a kappa
  • Application Notes
    This antibody binds to amyloid beta peptides and may be used in Western Blotting as well as ELISA and IHC. Youn et al. (PMID: 31077246) describes the use of an HRP-conjugate of the IgG2a version of WO2 in a diagnostic Multimer Detection System-Oligomeric Amyloid-β assay to measure oligomerization tendencies in the blood.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % Proclin 300.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Brai, Stuart, Badin, Greenfield: "A Novel Ex Vivo Model to Investigate the Underlying Mechanisms in Alzheimer's Disease." in: Frontiers in cellular neuroscience, Vol. 11, pp. 291, (2017) (PubMed).

  • Target
    Amyloid beta (4-10)
    Background
    Abeta
    UniProt
    P05067
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