Recombinant MS4A1 (Rituximab Biosimilar) antibody
Quick Overview for Recombinant MS4A1 (Rituximab Biosimilar) antibody (ABIN5668183)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-CD20 [10F381 (rituximab)], Rabbit IgG, kappa
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Specificity
- CD20 (Human B-lymphocyte-restricted differentiation antigen, Bp35), is a hydrophobic transmembrane protein with a molecular weight of approximately 35 kDa located on pre-B and mature B lymphocytes, and most B-cell non-Hodgkin's lymphomas, but is not found on stem cells, pro-B cells, normal plasma cells or other normal tissues .
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Cross-Reactivity
- Cynomolgus, Rhesus Monkey
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Characteristics
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Original Species of Ab: Human
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Purity
- > 98 % as determined by SDS-PAGE
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Endotoxin Level
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
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Immunogen
- Human lymphoblastoid cell line SB.
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Isotype
- IgG kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- MS4A1 (Rituximab Biosimilar)
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Target Type
- Biosimilar
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Background
- Leu16, B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35 Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20
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UniProt
- P11836
Target
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