DNAJB11 antibody (AA 25-130)

Catalog No. ABIN5675017

The Rabbit Polyclonal anti-DNAJB11 antibody has been validated for WB and ELISA. It is suitable to detect DNAJB11 in samples from Human and Mouse.

Quick Overview for DNAJB11 antibody (AA 25-130) (ABIN5675017)

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJB11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DNAJB11 Antibody

Binding Specificity: AA 25-130

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNAJB11

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DNAJB11

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Alternative Name: DNAJB11

Background:

Synonyms: DnaJ homolog subfamily B member 11, DNAJB11, APOBEC1-binding protein 2, ABBP-2, DnaJ protein homolog 9, ER-associated DNAJ, EDJ, ERJ3, HDJ9, PSEC0121, UNQ537/PRO1080

Background: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

Gene ID: 51726

UniProt: Q9UBS4

Pathways: ER-Nucleus Signaling