PSME1 antibody (AA 181-249)

Catalog No. ABIN5675558

This anti-PSME1 antibody is a Rabbit Polyclonal antibody detecting PSME1 in WB, ELISA, IF (cc), IF (p), IHC (p), ICC and IHC (fro). Suitable for Mouse, Rat and Cynomolgus.

Quick Overview for PSME1 antibody (AA 181-249) (ABIN5675558)

Target: PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))

Reactivity: Mouse, Rat, Cynomolgus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSME1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PSME1 Antibody

Binding Specificity: AA 181-249

Cross-Reactivity: Cynomolgus, Mouse, Rat

Predicted Reactivity: Human,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PSME1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PSME1

Target: PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))

Alternative Name: PSME1

Background:

Synonyms: 11S regulator complex alpha subunit, 11S regulator complex subunit alpha, 29 kD MCP activator subunit, 29kD MCP activator subunit, Activator of multicatalytic protease subunit 1, IFI5111, IGUP I-5111, Interferon gamma IEF SSP 5111, Interferon gamma inducible protein 5111, Interferon gamma up regulated I 5111 protein, Interferon gamma up-regulated I-5111 protein, MGC8628, PA28a, PA28alpha, Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha), Proteasome activator 28 subunit alpha, Proteasome activator complex subunit 1, Proteasome activator subunit 1, PSME1, PSME1_HUMAN, REG-alpha, REGalpha

Background: Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

Gene ID: 5720

UniProt: Q06323

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA