PTPRU antibody (AA 579-749)

Catalog No. ABIN5684107

The Mouse Monoclonal anti-PTPRU antibody has been validated for ELISA. It is suitable to detect PTPRU in samples from Human.

Quick Overview for PTPRU antibody (AA 579-749) (ABIN5684107)

Target: PTPRU (Protein Tyrosine Phosphatase, Receptor Type, U (PTPRU))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTPRU antibody is un-conjugated

Application: ELISA

Clone: 1A6E5

Product Details anti-PTPRU Antibody

Binding Specificity: AA 579-749

Purpose: PTPRU Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PTPRU (AA: 579-749) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PTPRU

Target: PTPRU (Protein Tyrosine Phosphatase, Receptor Type, U (PTPRU))

Alternative Name: PTPRU

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.

Molecular Weight: 162.4 kDa

UniProt: Q92729