PTPRD antibody (AA 1077-1265)

Catalog No. ABIN5684147

Product Details anti-PTPRD Antibody

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Binding Specificity: AA 1077-1265

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTPRD antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: PTPRD Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PTPRD (AA: 1077-1265) expressed in E. Coli.

Clone: 5H5D7

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PTPRD

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Alternative Name: PTPRD (PTPRD Products)

Background:

Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.

Aliases: HPTP, PTPD, HPTPD, HPTPDELTA, RPTPDELTA

Molecular Weight: 214.8kDa

Gene ID: 5789

HGNC: 2204

UniProt: P23468

Pathways: Synaptic Membrane