PTPRD antibody (AA 475-574)

Catalog No. ABIN6146458

This Rabbit Polyclonal antibody specifically detects PTPRD in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for PTPRD antibody (AA 475-574) (ABIN6146458)

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PTPRD Antibody

Binding Specificity: AA 475-574

Sequence: QITTIGNLVP QKTYSVKVLA FTSIGDGPLS SDIQVITQTG VPGQPLNFKA EPESETSILL SWTPPRSDTI ANYELVYKDG EHGEEQRITI EPGTSYRLQG

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 475-574 of human PTPRD (NP_002830.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRD

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Alternative Name: PTPRD

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.,PTPRD,HPTP,HPTPD,HPTPDELTA,PTPD,RPTPDELTA,Signal Transduction,Neuroscience,PTPRD

Molecular Weight: 156 kDa/169 kDa/212 kDa/214 kDa

Gene ID: 5789

UniProt: P23468

Pathways: Synaptic Membrane